Lonidamine: a new pharmacological approach to the study and control of spermatogenesis and tumors.
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منابع مشابه
Potentiation of radiation effects on two murine tumors by lonidamine.
Lonidamine is a potent inhibitor of spermatogenesis and a hyperthermic sensitizer. The principal established locus of biochemical action of lonidamine is a selective inhibitory effect of the energy metabolism either in NAD-linked reactions in germ cell mitochondria, as well as the glycolytic metabolism of a variety of tumor cell lines by means of inhibition of mitochondrially bound hexokinase. ...
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عنوان ژورنال:
- Chemotherapy
دوره 27 Suppl 2 شماره
صفحات -
تاریخ انتشار 1981